Table 2021
| Pos | Club | P | W | D | L | F | A | GD | Pts |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  Chainat Hornbill | 34 | 18 | 8 | 8 | 62 | 38 | 24 | 62 |
| 2 |  Ranong United | 33 | 15 | 9 | 9 | 51 | 40 | 11 | 54 |
| 3 |  Udon Thani | 33 | 15 | 8 | 10 | 61 | 42 | 19 | 53 |
| 4 |  Phrae United | 33 | 13 | 12 | 8 | 43 | 29 | 14 | 51 |
| 5 |  Lampang | 33 | 11 | 13 | 9 | 50 | 37 | 13 | 46 |
| 6 |  Nakhon Pathom United | 33 | 11 | 13 | 9 | 50 | 42 | 8 | 46 |
| 7 |  Chiang Mai | 33 | 13 | 7 | 13 | 44 | 49 | -5 | 46 |
| 8 |  Trat | 17 | 13 | 4 | 0 | 33 | 13 | 20 | 43 |
| 9 |  Ayutthaya United | 33 | 11 | 7 | 15 | 38 | 48 | -10 | 40 |
| 10 |  Kasetsart | 34 | 10 | 8 | 16 | 31 | 43 | -12 | 38 |
| 11 |  Chiangmai United | 17 | 11 | 3 | 3 | 34 | 15 | 19 | 36 |
| 12 |  Khon Kaen | 33 | 10 | 6 | 17 | 38 | 48 | -10 | 36 |
| 13 |  Sukhothai | 17 | 10 | 5 | 2 | 43 | 26 | 17 | 35 |
| 14 |  Nongbua Pitchaya | 16 | 8 | 7 | 1 | 28 | 8 | 20 | 31 |
| 15 |  Lamphun Warriors | 17 | 8 | 6 | 3 | 27 | 16 | 11 | 30 |
| 16 |  Navy | 33 | 6 | 7 | 20 | 33 | 59 | -26 | 25 |
| 17 |  Khon Kaen United | 16 | 7 | 3 | 6 | 19 | 14 | 5 | 24 |
| 18 |  Muangkan United | 17 | 5 | 6 | 6 | 31 | 32 | -1 | 21 |
| 19 |  Sisaket | 16 | 5 | 5 | 6 | 22 | 22 | 0 | 20 |
| 20 |  Rayong | 17 | 6 | 2 | 9 | 23 | 24 | -1 | 20 |
| 21 |  Customs Ladkrabang United | 17 | 4 | 5 | 8 | 31 | 41 | -10 | 17 |
| 22 |  Customs United | 16 | 5 | 2 | 9 | 17 | 36 | -19 | 17 |
| 23 |  Uthai Thani | 16 | 3 | 4 | 9 | 14 | 21 | -7 | 13 |
| 24 |  Rajpracha | 17 | 1 | 9 | 7 | 15 | 27 | -12 | 12 |
| 25 |  Samut Sakhon | 17 | 0 | 1 | 16 | 9 | 77 | -68 | 1 |