Ubon United withdrew from the league after playing 16 games, and all their results were declared null and void.
Regional League Table 2009
| Pos | Club | P | W | D | L | F | A | GD | Pts |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  Loei City | 20 | 14 | 3 | 3 | 44 | 19 | 25 | 45 |
| 2 |  Nakhon Ratchasima | 20 | 12 | 7 | 1 | 50 | 21 | 29 | 43 |
| 3 |  Udon Thani | 20 | 10 | 5 | 5 | 45 | 21 | 24 | 35 |
| 4 |  Buriram | 20 | 8 | 7 | 5 | 28 | 20 | 8 | 31 |
| 5 |  Nakhon Phanom | 20 | 8 | 5 | 7 | 42 | 44 | -2 | 29 |
| 6 |  Surin | 20 | 7 | 7 | 6 | 27 | 20 | 7 | 28 |
| 7 |  Chaiyaphum United | 20 | 6 | 6 | 8 | 17 | 21 | -4 | 24 |
| 8 |  Mahasarakham | 20 | 5 | 5 | 10 | 29 | 42 | -13 | 20 |
| 9 |  Sakon Nakhon | 20 | 6 | 2 | 12 | 25 | 48 | -23 | 20 |
| 10 |  Mukdahan-Savannakhet | 20 | 3 | 10 | 7 | 25 | 33 | -8 | 19 |
| 11 |  Roi Et United | 20 | 2 | 1 | 17 | 19 | 62 | -43 | 7 |
| 12 |  Ubon United | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |